https://sisu.ut.ee/lcms_method_validation/course-introduction
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Practice-oriented on-line course on validation of analytical methods, specifically using LC-MS as technique.
The course covered the following topics:
- The concept, workflow and scope of validation;
- Selectivity and identity confirmation, both via LC and via MS;
- Linearity of signal, linear range, sensitivity and their relation to calibration;
- Precision, trueness, accuracy, analyte stability and their interrelations;
- Limit of detection and limit of quantitation;
- Ruggedness and robustness.
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